This reference design is a low standby and ship-mode current consumption and high cell voltage accuracy 10s–16s Lithium-ion (Li-ion): LiFePO4 battery pack design. It monitors each cell voltage: pack current: cell and MOSFET temperature with high accuracy and protects the Li-ion: LiFePO4 battery pack against cell overvoltage: cell undervoltage: overtemperature: charge and discharge over current and discharge short-circuit situations. It adopts high-side N-channel MOSFET architecture and has strong driving on and off capability. Through an efficient auxiliary power supply strategy: this reference design achieves 100-μA standby and 10-μA ship mode consumption: saving more energy and allowing longer shipping time and idle time. These features make this reference design highly applicable for e-bike and e-scooter battery pack applications.