This reference design demonstrates how to create an industrial sensor-to-cloud end node capable of connecting to an IoT network gateway and a cloud data provider. This sensor node reference design uses Texas Instruments' nano-power system timer for power gating: low Iq boost converter: SimpleLink™ultra-low-power Sub-1 GHz wireless microcontroller (MCU) platform and humidity sensing technologies to demonstrate an ultra-lowpower method to duty-cycle sensor end-nodes: leading to longer battery life.